The following conditions and diseases can lead to an immunodeficiency disorder. Chronic lung diseases including COPD chronic obstructive pulmonary disease asthma moderate-to-severe interstitial lung disease cystic fibrosis and pulmonary hypertension Chronic lung diseases can make you more likely to get severely ill from COVID-19.
Evaluation Of Primary Immunodeficiency Disease In Children American Family Physician
Without a functional immune response people with PIDDs may be subject to chronic debilitating infections such as Epstein-Barr virus EBV which can increase the risk of developing cancer.
Immunocompromised diseases list. Blood Disorders Bone Joint and Muscle Disorders Brain Spinal Cord and Nerve Disorders Cancer Childrens Health Issues Digestive Disorders Disorders of Nutrition Drugs Ear Nose and Throat Disorders Eye Disorders Fundamentals Heart and Blood Vessel Disorders Hormonal and Metabolic Disorders Immune Disorders Infections Injuries and Poisoning Kidney and Urinary Tract Disorders Liver and Gallbladder Disorders Lung and Airway Disorders Mens Health Issues Mental Health Disorders. Alopecia areata - Not a rare disease. And those with inherited diseases that affect the immune system eg congenital agammaglobulinemia congenital IgA deficiency.
The following diseases and conditions are linked to primary immunodeficiency disorders. Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency. Familial hemophagocytic lymphohistiocytosis an autosomal recessive primary immunodeficiency is another example.
Graves disease Hashimoto thyroiditis rheumatoid arthritis Crohn disease ulcerative colitis systemic lupus erythematosus and multiple sclerosis are discussed in this article. We may eventually learn whether or not some vaccines are more effective for some people than others. Simply having an infection.
NIAID scientists and their collaborators identified the disease in 2014. CTLA4 deficiency is a rare disorder that severely impairs the normal regulation of the immune system resulting in conditions such as intestinal disease respiratory infections autoimmune problems and enlarged lymph nodes liver and spleen. In this case experts could modify vaccination strategies accordingly.
Type 1 diabetes Even well-controlled diabetics are immunocompromised to a degree says Mark Schutta MD an endocrinologist and medical director at Penn Rodebaugh Diabetes Center. Common autoimmune diseases include. Autoimmune conditions turn immune cells into double agents that fight against your own healthy tissues.
People whose immune systems are compromised by immunodeficiency diseases autoimmune diseases or by taking certain medications will not be able to make as good an immune response as young healthy people. One example is common variable immunodeficiency CVID where multiple autoimmune diseases are seen eg inflammatory bowel disease autoimmune thrombocytopenia and autoimmune thyroid disease. Read more about CTLA4 deficiency.
McGorry builds off of this list saying A lot of autoimmune diseases that we treat in rheumatology take a toll on the patients immune system such as systemic lupus erythematosus. Ataxia-telangiectasia Chediak-Higashi syndrome combined immunodeficiency disease complement deficiencies DiGeorge syndrome hypogammaglobulinemia Job syndrome leukocyte adhesion defects panhypogammaglobulinemia. For example for people of different age groups with immunodeficiencies autoimmune disease.
Any infections including bacterial infections mycobacterial infections such as tuberculosis and viral infections for example HIVAIDS measles herpes glandular fever EBV CMV and chickenpox Chronic diseases like diabetes type 1 or type 2 kidney failure liver cirrhosis and liver failure. Primary immune deficiency diseases PIDDs are rare genetic disorders that impair the immune system. Cancer and transplant patients who are taking certain immunosuppressive drugs.
PIDDs may be diagnosed in infancy childhood or adulthood depending on disease. Some PIDDs can be fatal. Examples of persons with weakened immune systems include those with HIVAIDS.
IgG4-related systemic disease IgG4-related sclerosing disease IgG4. Who might be immunocompromised or have a weakened immune system.
